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eMediNexus 08 December 2021
Currently, the prevalence of nonalcoholic fatty liver disease (NAFLD) in children with obesity is described ranging from 1.7% to 85%.
Thus a study investigated its prevalence and evaluated the diagnostic accuracy of alanine aminotransferase (ALT) for NAFLD in children with obesity.
The study investigated the presence of NAFLD in children aged 9-17 years with obesity.
Other diseases were excluded by history and laboratories. Liver magnetic resonance imaging proton density fat fraction was utilized to measure Hepatic steatosis. Further, the diagnostic accuracy of ALT for detecting NAFLD was assessed.
The following observations were made-
Thus NAFLD was found to be commonly reported in children with obesity, but NAFLD and obesity were not found to be connected. NAFLD is present in nearly one-third of boys and one-fourth of girls, with obesity.
Source: The Journal of Pediatrics,2019;207:64-70. https://doi.org/10.1016/j.jpeds.2018.11.021.
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